Пропаргилового спирта химические свойства, назначение, производство
Химические свойства
Propargyl alcohol is a colorless liquid with a
geranium-like odor.
Использование
Propargyl alcohol is a solvent stabilizer that is useful as an intermediate in organic synthesis, an electroplating brightener additive. It is useful 3-carbon fragment in acetylene coupling reactions, It undergoes Pd-catalyzed O-coupling with alcohols to give the corresponding 1-methoxyallyl ethers.
Методы производства
Propargyl alcohol is the major commercially available acetylenic
primary alcohol. Propargyl alcohol is a byproduct
of butynediol production. In the usual high-pressure
butynediol process, about 5% of the product is propargyl
alcohol. Some processes give higher proportions of propargyl
alcohol.
Определение
ChEBI: A terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1.
Общее описание
A dark liquid with a "fishlike" odor. Less dense than water. Flash point 90°F. Boiling point is 239°F. Corrosive and contact may severely irritate skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.
Реакции воздуха и воды
Highly flammable. Soluble in water.
Опасность
Flammable, moderate fire risk. Toxic by
ingestion, inhalation, and skin absorption. Eye irri-
tant, liver and kidney damage.
Угроза здоровью
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Пожароопасность
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Профиль безопасности
Poison by ingestion,
skin contact, and subcutaneous routes.
Moderately toxic by inhalation. A central
nervous system depressant. A skin and
mucous membrane irritant. Mutation data
reported. Flammable liquid and dangerous
fire hazard when exposed to heat or flame;
can ignite. To fight fire, use foam, CO2, dry
chemical. Potentially explosive reactions
with alkalies (when dried), sulfuric acid.
Ignites on contact with phosphorus
pentaoxide. Violent reaction with
mercury(Ⅱ) sulfate + sulfuric acid + water
(at 70°C). Incompatible with oxidizing
materials. When heated to decomposition it
emits acrid smoke and irritating fumes. Used
as a corrosion inhibitor, solvent stabilizer,
soil fumigant, and chemical intermediate.
See also ACETYLENE COMPOUNDS.
Возможный контакт
Propargyl alcohol is used as
a corrosion inhibitor, soil fumigant; solvent, stabilizer, and
chemical intermediate.
хранилище
2-Propyn-1-ol is stored in stainless steellined, glass-lined, or phenolic-lined tanks ordrums. Unlined steel containers may be usedif free of rust. Aluminum, rubber, and epoxymaterials should not be used. Use protectivewear when handling. Wash thoroug.
Перевозки
UN1986 Alcohols, flammable, toxic, n.o.s.,
Hazard Class: 3; Labels: 3-Flammable liquid, 6.1-
Poisonous materials, Technical Name Required. UN2929
Toxic liquids, flammable, organic, n.o.s., Hazard class: 6.1;
Методы очистки
The commercial material contains a stabiliser. An aqueous solution of propargyl alcohol can be concentrated by azeotropic distillation with butanol or butyl acetate. Dry it with K2CO3 and distil it under reduced pressure, in the presence of about 1% succinic acid, through a glass helices-packed column. [Beilstein 1 IV 2214.]
Несовместимости
Vapor may form explosive mixture with
air. Incompatible with oxidizers (chlorates, nitrates, perox-
ides, permanganates, perchlorates, chlorine, bromine, fluo-
rine, etc.); contact may cause fires or explosions. Keep
away from alkaline materials, strong bases, strong acids,
oxoacids, epoxides, phosphorus pentoxide. May polymerize
under the influence of heat, oxidizers, peroxides, light.
Attacks many plastics.
Утилизация отходов
Wear protective eye protec-
tion, gloves and clothing to prevent any reasonable proba-
bility of skin or eye contact. Safety equipment suppliers/
manufacturers can provide recommendations on the most
protective glove/clothing material for your operation. All
protective clothing (suits, gloves, footwear, headgear)
should be clean, available each day, and put on before
work. Contact lenses should not be worn when working
with this chemical. Wear splash-proof chemical goggles
and face shield when working with liquid full facepiece
respiratory protection is worn. Employees should wash
immediately with soap when skin is wet or contaminated.
Provide emergency showers and eyewash.
Пропаргилового спирта препаратная продукция и сырье
сырьё
препарат