N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- CAS:
- 1207360-89-1
- MF:
- C24H32N6O3
- MW:
- 452.55
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Company Type
Properties
- Boiling point:
- 571.3±50.0 °C(Predicted)
- Density
- 1.269
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 10 mg/ml
- form
- Powder
- pka
- 13.87±0.46(Predicted)
- color
- Light yellow to yellow
Safety Information
Use
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is a potent and selective mTOR inhibitor with dose-dependent efficacy in mouse x enograft cancer models.
0 India supplier list of "N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea"
- Product Name:N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- Products Intro:Purity: 95-99% | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:GDC-0349;GDC0349;RG-7603;GDC 0349
- Products Intro:Package: 1 mL * 10mM (in DMSO);10 mg;2 mg;25 mg;5 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:GDC-0349
- Products Intro:Purity: >=99% | Package: $142.9/5mg;$234.9/10mg;$528.9/25mg;$1031.9/50mg;$1857.9/100mg;Bulk package | CustNote: 99%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
-
10mg$270.0025mg$540.00
- Product Name:(S)-1-Ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
- Products Intro:Brand: Matrix Scientific | Product Number: 132331 | Purity: 97%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof