2,6-Dichlorothiobenzamide
2,6-Dichlorothiobenzamide
- CAS:
- 1918-13-4
- MF:
- C7H5Cl2NS
- MW:
- 206.09
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Properties
- Melting point:
- 151-152°C
- Boiling point:
- 320.6±52.0 °C(Predicted)
- Density
- 1.4704 (rough estimate)
- refractive index
- 1.6300 (estimate)
- Flash point:
- >100 °C
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 11.71±0.29(Predicted)
- color
- White to Pale Beige
- Water Solubility
- 0.95g/L(21 ºC)
- BRN
- 1910353
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 36
- WGK Germany
- 1
- RTECS
- CV3850000
- Hazard Note
- Harmful
- HazardClass
- IRRITANT
- HS Code
- 2930909899
- Toxicity
- LD50 oral in rabbit: 300mg/kg
Use
Twelve metabolites are isolated from either urine or bile from either rats (11 metabolites) or goats (seven metabolites) given single oral doses of 14C-labeled 2,6-dichlorobenzonitrile (DCBN). Five of these metabolites are also excreted in urine from rats dosed orally with 2,6-dichlorothiobenzamide (DCTBA) which is an acid amide analog. All metabolites from either DCBN or DCTBA are benzonitriles with the following ring substituents: Cl2, OH (three isomers); Cl2, (OH)2; Cl, (OH)2; Cl, OH, SH; Cl, OH, SCH3; SOCH3, OH; Cl2, S-(N-acetyl)cysteine; Cl, S-(N-acetyl)cysteine; Cl, OH, S-(N-acetyl)cysteine. The thiobenzamide moiety of DCTBA is converted to the nitrile in all extracted urinary metabolites. No hydrolysis of the nitrile in DCBN to either amide or an acid is detected. Urine is the major route for excretion; however, enterohepatic circulation occurs.
0 India supplier list of "2,6-Dichlorothiobenzamide"
- Product Name:Chlorthiamid
- Products Intro:Brand:sigma aldrich | Product Number:45398 | Purity:PESTANAL?,analyticalstandard
- Company Type: Trader
- Country/Region: Bangalore,INDIA