8-pCPT-2μ-O-Me-cAMP
8-pCPT-2μ-O-Me-cAMP
- CAS:
- 634207-53-7
- MF:
- C17H16ClN5NaO6PS
- MW:
- 507.82
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Properties
- Melting point:
- 235.5-237.5 °C(lit.)
- storage temp.
- −20°C
- solubility
- H2O: >10mg/mL
- form
- solid
- color
- white
- Water Solubility
- Soluble to 100 mM in water
Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
Use
]Exchange proteins activated by cAMP (Epacs) are guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-pCPT-2'-O-Me-cAMP is a super-activator of Epacs in that it dissociates GDP from Rap1 more strongly than the natural Epac agonist, cAMP. 8-pCPT-2'-O-Me-cAMP is strongly selective for Epac over the cAMP-activated kinase PKA. It does not discriminate between Epac1 and Epac2 and is used extensively to elucidate the roles of these Rap GEFs in cell function.[Cayman Chemical]
0 India supplier list of "8-pCPT-2μ-O-Me-cAMP"
- Product Name:8-(4-Chlorophenylthio)-2′-O-methyladenosine3′,5′-cyclicmonophosphatemonosodiumhydrate
- Products Intro:Brand:sigma aldrich | Product Number:C8988 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA