Clemastine fumarate
Clemastine fumarate
- CAS:
- 14976-57-9
- MF:
- C25H30ClNO5
- MW:
- 459.96
Suppliers by country/region
Company Type
Properties
- Melting point:
- 158-162°C
- alpha
- D21 +16.9° (methanol)
- Boiling point:
- 154°C (rough estimate)
- Density
- 1.0247 (rough estimate)
- refractive index
- 1.5790 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble5mg/mL (clear solution; warmed)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +15 to +25°, c = 1 in methanol
- InChIKey
- PMGQWSIVQFOFOQ-YKVZVUFRSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
- WGK Germany
- 3
- RTECS
- UY0704600
- HS Code
- 2933992600
- Toxicity
- LD50 in mice, rats (mg/kg): 730, 3550 orally; 43, 82 i.v. (Weimann)
Use
Clemastine fumarate is a selective histamine H1 receptor antagonist (Ki = 0.26 nM) that also displays high affinity for muscarinic receptors (Ki = 16 nM). It has also recently been identified as a positive allosteric modulator of P2X7 receptor signaling. Clemastine fumarate has long been used to inhibit histamine-induced bronchoconstriction in asthma and airway hyperresponsive studies.
3 India supplier list of "Clemastine fumarate"
- Product Name:Clemastinefumaratesalt
- Products Intro:Brand:sigma aldrich | Product Number:SML0445 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Clemastine fumarate >99% (HPLC), powder
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.072210
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:ClemastineFumarate
- Products Intro:Brand:synzeal | Product Number:147363424
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:ClemastineFumarate
- Products Intro:Brand:clearsynth | Product Number:CS-O-06237
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Clemastinefumarate
- Products Intro:Brand:ajchemicals | Product Number:JDH-27767 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Clemastine fumarate
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Clemastine fumarate
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:ClemastineFumarate
- Products Intro:Brand:pharmaffiliates | Product Number:PA5642000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Clemastine fumarate
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$0.00/ 25KG
- Product Name:Clemastine fumarate
- Products Intro:Purity: 98%|Package: 1kg;10.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Povidone Iodine,Lenvatinib mesylate,1,2,3-Triacetyl-5-deoxy-D-ribose,Diethyl L-glutamate hydrochloride,Pregabalin
$10.00/ 1kg