Exemestane
Exemestane
- CAS:
- 107868-30-4
- MF:
- C20H24O2
- MW:
- 296.4
Suppliers by country/region
Company Type
Properties
- Melting point:
- 155.13°C
- Boiling point:
- 453.7±45.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- color
- white to off-white
- optical activity
- [α]/D +250 to +300°, c = 1 in methanol
- InChI
- InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
- InChIKey
- BFYIZQONLCFLEV-DAELLWKTSA-N
- SMILES
- C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=O)CC3)CC2=C
Safety Information
- Symbol(GHS)
GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H360-H411
- Precautionary statements
- P201-P202-P273-P280-P308+P313-P391
- Hazard Codes
- T,N
- Risk Statements
- 60-61-51
- Safety Statements
- 53-22-36/37-57
- WGK Germany
- 3
- HS Code
- 29372900
Use
For patients resistant to tamoxifen, 25mg of Exemestane, qd, can achieve an objective efficacy rate of 15-28% and a median continuation period of 69-76 weeks. Exemestane is superior to Megestrol, and it can extend the disease progression time. For patients who have worsened conditions following Megestrol treatment, Exemestane can still achieve an objective efficacy rate of 11-13%. A daily 25mg dose of Exemestane has an objective efficacy rate of 6.6% on patients who have not responded to non-steroidal aromatase inhibitors, and the two drugs are not cross-resistant.
54 India supplier list of "Exemestane"
- Product Name:Exemestane
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Exemestane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Exemestane
- Products Intro:Brand:sigma aldrich | Product Number:PHR1634 | Purity:PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
- Company Type: Trader
- Country/Region: Bangalore,INDIA