Nilvadipine manufacturers and suppliers in india

Nilvadipine

Properties

Melting point:: 148-150°C

Boiling point:: 511.83°C (rough estimate)

Density: 1.3937 (rough estimate)

refractive index: 1.5900 (estimate)

storage temp.: Keep in dark place,Sealed in dry,2-8°C

solubility: DMSO: soluble15mg/mL, clear

form: powder

pka: -0.81±0.70(Predicted)

color: white to beige

Merck: 14,6545

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302+H312+H332-H315-H319

Precautionary statements: P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312

Hazard Codes: Xn

Risk Statements: 22

WGK Germany: 3

RTECS: US7968300

HS Code: 2933.39.9200

Toxicity: LD50 oral in rat: 1560mg/kg

Use

Nilvadipine is a new, second-generation calcium channel blocker effective in the treatment of hypertension and angina pectoris. Its potent inhibitory effect on the stimulated chemotaxis of smooth muscle cells and protective action against calcium deposition suggest that nilvadipine may be useful for preventing and treating atherosclerosis.