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Olaparib

Olaparib

CAS:
763113-22-0
MF:
C24H23FN4O3
MW:
434.46

Properties

Density 
1.43
storage temp. 
-20°C
solubility 
Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
pka
12.07±0.40(Predicted)
form 
solid
color 
Off-white
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey
FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)=NN1

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS05
Signal word 
Danger
Hazard statements 
H314
Precautionary statements 
P501-P260-P264-P280-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P405
Risk Statements 
22-38-37-36
Safety Statements 
24/25-37/39
HazardClass 
IRRITANT
HS Code 
29339900

Use

Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy.

8 India supplier list of "Olaparib"

Zyphars Biopharmaceuticals Pvt. Ltd
  • Product Name:Olaparib
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Mumbai,INDIA
Dr. Reddy's Laboratories Ltd
  • Product Name:Olaparib (Form A)
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
Lupin Ltd
  • Product Name:Olaparib
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
Alembic Pharmaceuticals Limited
  • Product Name:Olaparib
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Olaparib 95%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.171501
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
SynZeal Research Pvt Ltd
  • Product Name:Olaparib
  • Products Intro:Brand:synzeal | Product Number:115318455
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:OLAPARIB
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Olaparib
  • Products Intro:Brand:clearsynth | Product Number:CS-O-11822
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
Clearsynth Labs Research Centre
  • Product Name:Olaparib (AZD2281, Ku-0059436)
  • Company Type: Reagent
  • Country/Region: Mallapur,INDIA
  • Product Name:OLAPARIB
  • Company Type: Manufacturer
  • Country/Region: New Delhi,INDIA

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