Topiroxostat
Topiroxostat
- CAS:
- 577778-58-6
- MF:
- C13H8N6
- MW:
- 248.24
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 594.7±60.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 23.5 mg/mL (94.67 mM; Need ultrasonic and warming)
- form
- Powder
- pka
- 7.47±0.10(Predicted)
- color
- White to off-white
- InChI
- InChI=1S/C13H8N6/c14-8-11-7-10(3-6-16-11)13-17-12(18-19-13)9-1-4-15-5-2-9/h1-7H,(H,17,18,19)
- InChIKey
- UBVZQGOVTLIHLH-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC=CC(C2NN=C(C3C=CN=CC=3)N=2)=C1
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Use
Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme results in efficacious reduction of serum urate levels. Approved for therapeutic use in Japan since 2013, topiroxostat is marketed under the name Topiloric and Uriadec and is orally administered twice daily.
1 India supplier list of "Topiroxostat"
- Product Name:Topiroxostat
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Topiroxostat
- Products Intro:Brand:synzeal | Product Number:212495347
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Topiroxostat
- Products Intro:Purity: 99.0% min | Package: 1kg;|10kg;|100kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2-Chloromalonaldehyde,(R)-5,7-difluorochroman-4-ol,Cyclobutanecarboxylic acid,(Bromomethyl)cyclobutane,5-Amino-4-imidazolecarboxamide
$0.00-0.00 / 1kg
- Product Name:Topiroxostat
- Products Intro:Purity: 98.0% | Package: 1KG;0.1USD
- Company Type: Trader
- Country/Region: CHINA
$0.10/ 1KG
- Product Name:Topiroxostat
- Products Intro:Purity: 98% HPLC | Package: 1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride
$0.00/ 1g