Acridine manufacturers and suppliers in india

Acridine

Properties

Melting point:: 106-109 °C

Boiling point:: 346 °C(lit.)

Density: 1,005 g/cm³

refractive index: 1.7270 (estimate)

Flash point:: 346°C

storage temp.: Refrigerator

solubility: dioxane: 0.1 g/mL, clear

pka: 5.58(at 20℃)

form: Crystalline Powder

color: Yellow to yellow-brown

PH Range: Green B uorescence (5.2) to violet B uorescence (6.6)

Water Solubility: 57.35mg/L(24 ºC)

λmax: 358nm, 392nm

Merck: 14,122

BRN: 120200

Exposure limits: OSHA: TWA 0.2 mg/m3

Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.

Major Application: Organic light-emitting diode, photoresists, nanosensors, fuel cells, memory device, semiconductors, information storage device, liquid crystal displays, identification of product forgeries, inks, adhesives, textile, hair dyes, gene detection assay, staining cells, biosensors, detecting nucleic acids, proteins, antiHCV antibodies, antibacterial, antiamyloid agents, wound dressing materials, vaccines against infection, allergy and cancer

InChIKey: DZBUGLKDJFMEHC-UHFFFAOYSA-N

LogP: 3.400

Safety Information

Symbol(GHS): GHS07,GHS09

Signal word: Warning

Hazard statements: H302-H315-H319-H335-H410

Precautionary statements: P261-P264-P273-P301+P312-P302+P352-P305+P351+P338

Hazard Codes: Xn

Risk Statements: 22-68-36/37/38

Safety Statements: 22-36-45-36/37/39-26

RIDADR: UN 2713 6.1/PG 3

WGK Germany: 3

RTECS: AR7175000

TSCA: Yes

HazardClass: 6.1

PackingGroup: III

HS Code: 29333990

Toxicity: LD50 s.c. in mice: 0.40 g/kg (Rubbo)

Use

Acridine has been crystallised twice from *benzene/cyclohexane, or from aqueous EtOH, then sublimed, removing and discarding the first 25% of the sublimate. The remainder is again crystallised and sublimed, discarding the first 10-15% [Wolf & Anderson J Am Chem Soc 77 1608 1955]. Acridine can also be purified by crystallisation from n-heptane and then from ethanol/water after pre-treatment with activated charcoal, or by chromatography on alumina with pet ether in a darkened room. Alternatively, acridine can be precipitated as the hydrochloride from *benzene solution by adding HCl, after which the base is regenerated, dried at 110o/50mm, and recrystallised to constant melting point from pet ether [Cumper et al. J Chem Soc 4518 1962]. The regenerated free base may be recrystallised, chromatographed on basic alumina, then vacuum-sublimed and zone-refined. [Williams & Clarke, J Chem Soc, Faraday Trans 1 73 514 1977, Albert, The Acridines Arnold Press 1966.] It can exist in five crystalline forms and is steam volatile. It is a strong IRRITANT to skin and mucous membranes and can become a chronic irritant— handle it with CARE. [Beilstein 20/8 V 199.]