Ampicillin
Ampicillin
- CAS:
- 69-53-4
- MF:
- C16H19N3O4S
- MW:
- 349.4
Suppliers by country/region
Company Type
Properties
- Melting point:
- 198-200 °C (dec.)(lit.)
- alpha
- D23 +287.9° (c = 1 in water)
- Boiling point:
- 201.8°C (rough estimate)
- Density
- 1.2794 (rough estimate)
- refractive index
- 1.6320 (estimate)
- storage temp.
- 2-8°C
- solubility
- NH4OH 1 M: 50 mg/mL, clear, colorless
- form
- solid
- color
- White to Pale Yellow
- pka
- 2.5 (COOH)(at 25℃)
- Water Solubility
- 13.9g/L(25 ºC)
- JECFA Number
- 85
- Merck
- 13,591
- BRN
- 1090925
- Stability:
- Stable, but may be moisture sensitive. Incopmpatible with strong oxidizing agents.
- InChIKey
- AVKUERGKIZMTKX-NJBDSQKTSA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H317-H334
- Precautionary statements
- P261-P272-P280-P284-P302+P352-P333+P313
- Hazard Codes
- Xn,T
- Risk Statements
- 36/37/38-42/43-61
- Safety Statements
- 22-26-36/37-45-53
- WGK Germany
- 2
- RTECS
- XH8425000
- F
- 10-23
- HS Code
- 29212900
- Toxicity
- LD50 oral in mouse: > 5gm/kg
Use
Ampicillin is a β-lactam antibiotic within the penicillin family. As a member of this family, Ampicillin is susceptible to β-lactamase, which hydrolyzes the β-lactam ring. This broad spectrum antibiotic is effective against gram-positive, gram-negative bacteria and anaerobic bacteria. Ampicillin is widely used in cell culture as a selective agent. As an antibiotic, Ampicillin binds to penicillin binding proteins (PBPs) on a susceptible organism and Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. After binding to the PBPs, Ampicilin acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and thereby prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium.
50 India supplier list of "Ampicillin"
- Product Name:Piperacillin EP Impurity A
- Products Intro:Purity: 98% | Package: 25mg; 50mg; 100mg; Customised
- Company Type: Trader
- Country/Region: Punjab,INDIA
- Product Name:Ampicillin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Ampicillin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Ampicillin
- Products Intro:Brand:sigma aldrich | Product Number:A5354 | Purity:ReadyMadeSolution,100?mg/mL,0.2μmfiltered
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Ampicillin
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA