BIIB-021
BIIB-021
- CAS:
- 848695-25-0
- MF:
- C14H15ClN6O
- MW:
- 318.76
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Properties
- Melting point:
- 192-193℃
- Boiling point:
- 588.5±60.0 °C(Predicted)
- Density
- 1.50
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (>25 mg/ml)
- pka
- 6.07±0.40(Predicted)
- form
- solid
- color
- White
- Stability:
- Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 montha.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P271-P280
- HS Code
- 2921490090
Use
BIIB 021 an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90. Studies show that BIIB 021 adminisitration led to degradation of Hsp90 client proteins measured in tumor tissue and resulted in the inhibition of tumor growth in several human tumor xenograft models.
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