Caspofungin
Caspofungin
- CAS:
- 162808-62-0
- MF:
- C52H88N10O15
- MW:
- 1093.31
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 1408.1±65.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- pka
- 9.86±0.26(Predicted)
Safety Information
Use
Cmax 70 mg 1-h infusion: c. 10 mg/L 1 h post infusion Plasma half-life: 9–11 h Volume of distribution: 0.15 L/kg Plasma protein binding: 97% Blood concentrations increase in proportion to dosage. Distribution The drug is widely distributed, the highest concentrations being found in the liver. Levels in the CSF are negligible. Metabolism and excretion It is slowly metabolized by the liver through non-enzymatic peptide hydrolysis and N-acetylation, and the two inactive metabolites are excreted in the feces and bile. No dosage adjustment is required in patients with renal impairment; however, a dose reduction to 35 mg following the 70 mg loading dose is recommended for patients with moderate hepatic impairment. Caspofungin is not cleared by hemodialysis.
6 India supplier list of "Caspofungin"
- Product Name:Caspofungin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Caspofungin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Tamil Nadu,INDIA
- Product Name:Caspofungin
- Products Intro:Brand:clearsynth | Product Number:CS-O-07556
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Caspofungin
- Products Intro:Brand:synzeal | Product Number:250813961
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Caspofungin
- Company Type: Reagent
- Country/Region: Ahmedabad,INDIA
- Product Name:Caspofungin
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Caspofungin
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Caspofungin
- Products Intro:Brand:pharmaffiliates | Product Number:PA3087000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Caspofungin
- Company Type: Reagent
- Country/Region: Delhi,INDIA
- Product Name:Caspofungin
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes