Ceftizoxime sodium
Ceftizoxime sodium
- CAS:
- 68401-82-1
- MF:
- C13H14N5NaO5S2
- MW:
- 407.39
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Company Type
Properties
- Melting point:
- 227℃
- RTECS
- XI0368000
- storage temp.
- -20°C
- solubility
- DMSO: soluble1mg/mL
- form
- solid
- color
- white to faint yellow
- Water Solubility
- Soluble in water
- Stability:
- Unstable in Solution
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- Toxicity
- LD50 in mice, rats (mg/kg): ~6000 i.v. (Fukuhara)
Use
Ceftizoxime (Cefizox) is a third-generation cephalosporinthat was introduced in 1984. This β-lactamase–resistant agentexhibits excellent activity against the Enterobacteriaceae,especially E. coli, K. pneumoniae, E. cloacae, Enterobacteraerogenes, indole-positive and indole-negative Proteus spp.,and S. marcescens. Ceftizoxime is claimed to be more activethan cefoxitin against B. fragilis. It is also very active againstGram-positive bacteria. Its activity against P. aeruginosa issomewhat variable and lower than that of either cefotaxime orcefoperazone.Ceftizoxime is not metabolized in vivo. It is excretedlargely unchanged in the urine. Adequate levels of the drugare achieved in the cerebrospinal fluid for the treatment ofGram-negative or Gram-positive bacterial meningitis. It mustbe administered on a thrice-daily dosing schedule because ofits relatively short half-life. Ceftizoxime sodium is very stablein the dry state. Solutions maintain potency for up to 24hours at room temperature and 10 days when refrigerated.
3 India supplier list of "Ceftizoxime sodium"
- Product Name:Ceftizoximesodiumsalt
- Products Intro:Brand:sigma aldrich | Product Number:A3612
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Ceftizoxime Sodium
- Products Intro:Brand:synzeal | Product Number:204666684
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:CeftizoximeSodium
- Products Intro:Brand:pharmaffiliates | Product Number:PA034170000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Ceftizoxime sodium
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$0.00/ 25KG
- Product Name:Ceftizoxime Sodium
- Products Intro:Purity: 99% | Package: 1Kg
- Company Type: Trader
- Country/Region: CHINA
$0.00/ 1Kg