Eltrombopag
Eltrombopag
- CAS:
- 496775-61-2
- MF:
- C25H22N4O4
- MW:
- 442.47
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Properties
- Melting point:
- 242-244°C
- Boiling point:
- 656.8±65.0 °C(Predicted)
- Density
- 1.33
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Soluble in DMSO (up to 55 mg/ml) or in ethanol (up to 14 mg/ml).
- form
- solid
- pka
- -1.26±0.40(Predicted)
- color
- Orange
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
- InChI
- InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22-
- InChIKey
- XDXWLKQMMKQXPV-QYQHSDTDSA-N
- SMILES
- C1(C2=CC=CC(N/N=C3\C(=O)N(C4=CC=C(C)C(C)=C4)N=C\3C)=C2O)=CC=CC(C(O)=O)=C1
Safety Information
- Symbol(GHS)
GHS07,GHS08,GHS09,GHS05
- Signal word
- Danger
- Hazard statements
- H318-H373-H410-H302
- Precautionary statements
- P273-P391-P501-P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310-P260-P314-P501
Use
Eltrombopag (SB-497115-GR, Promacta, Revolade) is a small molecule agonist of the c-mpl (TpoR) receptor with an IC50 of 0.69 μM for the inhibition of hERG K+ channel tail current. In preclinical studies, the compound was shown to interact selectively with
10 India supplier list of "Eltrombopag"
- Product Name:Eltrombopag
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Eltrombopag
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Eltrombopag
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Eltrombopag
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Eltrombopag Free Acid
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Eltrombopag
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Eltrombopag 98% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.094685
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Eltrombopag
- Products Intro:Brand:synzeal | Product Number:953917497
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Eltrombopag13C4
- Products Intro:Brand:clearsynth | Product Number:CS-O-06578
- Company Type: Trader
- Country/Region: INDIA