ENDOTHAL
ENDOTHAL
- CAS:
- 145-73-3
- MF:
- C8H10O5
- MW:
- 186.16
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Properties
- Melting point:
- 179-180℃
- Boiling point:
- 447.8±40.0 °C(Predicted)
- Density
- 1.431 g/cm3
- storage temp.
- +2C to +8C
- solubility
- DMF: 15 mg/ml,DMSO: 15 mg/ml,Ethanol: 15 mg/ml,PBS (pH 7.2): 0.2 mg/ml
- pka
- 3.62±0.40(Predicted)
- form
- White solid
- color
- White to off-white
- Water Solubility
- Soluble in water (>25 mg/ml), methanol, acetone, and DMSO. Insoluble in benzene.
- Stability:
- Hygroscopic
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Warning
- Hazard statements
- H301-H312-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P310a-P305+P351+P338-P405-P501a
- Hazard Codes
- T
- Risk Statements
- 21-25-36/37/38
- Safety Statements
- 36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 1
- RTECS
- RN7875000
- HazardClass
- 6.1(a)
- PackingGroup
- II
- Toxicity
- LD50 in adult male, female rats (mg/kg): 57, 46 orally (Gaines, Linder)
Use
Biological. Incubation of 14C-ring labeled endothall (10 mg/mL) by Arthrobacter sp., which was isolated from pond water and a hydrosol, in aerobic sediment-water suspensions revealed that after 30 days, 40% evolved as 14CO2. Glutamic acid was the major transformation product. Minor products were alanine, citric and aspartic acids and unidentified products, some of which were tentatively identified as phosphate esters (Sikka and Saxena, 1973). In pond water treated with endothall (2 and 4 ppm), detectable levels were found after 7 days (Sikka and Rice, 1973). Biodegradation was rapid in an Ontario soil sample. After 1 week, 70% of endothall added was converted to carbon dioxide (Simsiman et al., 1976). Chemical/Physical. Reacts with bases forming water-soluble salts. Above 90°C, endothall is slowly converted to the anhydride (Windholz et al., 1983; Hartley and Kidd, 1987) and water (Humburg et al., 1989). Endothall is stable to light (Hartley and Kidd, 1987).
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