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Ephedrine
Ephedrine
- CAS:
- 299-42-3
- MF:
- C10H15NO
- MW:
- 165.24
Properties
- Melting point:
- 37-39 °C(lit.)
- Boiling point:
- 255 °C(lit.)
- alpha
- -41 º (c=5, 1M HCl)
- Density
- 1.124 g/mL at 25 °C(lit.)
- refractive index
- 1.4820 (estimate)
- Flash point:
- 186 °F
- storage temp.
- Refrigerator (+4°C)
- solubility
- Water (easy), ethanol (easy), ether (easy)
- pka
- pKa 8.02 (Uncertain);9.5 (Uncertain)
- optical activity
- [α]21/D 41°, c = 5 in 1 M HCl
- Water Solubility
- 47.62g/L(25 ºC)
- Merck
- 13,3639
- BRN
- 2208730
- Stability:
- Stable. Combustible. Incompatible with strong acids, acid chlorides, acid anhydrides, strong oxidizing agents. May discolour in light.
Safety Information
- Symbol(GHS)
GHS05,GHS07
- Signal word
- Danger
- Hazard statements
- H302-H314-H317
- Precautionary statements
- P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 22-25
- WGK Germany
- 1
- RTECS
- KB0700000
- F
- 3-10
- Hazard Note
- Harmful
- HS Code
- 29394100
- Toxicity
- LD50 oral in rat: 600mg/kg
Use
ephedrine: An alkaloid,C6H5CH(OH)CH(CH3)NHCH3 found inplants of the genus Ephedra, onceused as a bronchodilator in the treatmentof asthma. It is also used as astimulant and appetite suppressant.Structurally, it is a phenylethylamineand is similar to amphetamines, althoughless active. It is, however,widely used in the illegal synthesis ofmethamphetamine. The moleculehas two chiral centres. If the stereo- chemical conformations are opposite(i.e. 1R,2S or 1S,1R) the nameephedrine is used. If the conformationsare the same (1R,2R or 1S,2S)then the compound is called pseudoephedrine.
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