GRAMICIDIN A
GRAMICIDIN A
- CAS:
- 11029-61-1
- MF:
- C99H140N20O17
- MW:
- 1882.29
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Properties
- storage temp.
- 2-8°C
- solubility
- ethanol: soluble
- form
- White to off-white solid
- color
- colorless or white
- BRN
- 6461131
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
- Hazard Codes
- Xn
- Risk Statements
- 22
- WGK Germany
- 3
- RTECS
- MD8230000
- Toxicity
- mouse,LD50,intraperitoneal,60mg/kg (60mg/kg),"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 240, 1980.
Use
Purify gramicidin A by countercurrent distribution from *C6H6/CHCl3, MeOH/H2O (15:15:23:7) with 5000 tubes. Fractions are examined by UV (280nm) of small aliquots. Separation from gramicidin C and other material occurred after 999 transfers. [Gross & Witkop Biochemistry 4 2495 1965, Bauer et al. Biochemistry 11 3266 1972.] Purify it finally by recrystallisation from EtOH/H2O and dry it at 100o/10-2mm over KOH. It forms platelets m 229-230o. It is almost insoluble in H2O (0.6%) but soluble in lower alcohols, dry Me2CO, dioxane, acetic acid and pyridine. The commercial material is more difficult to crystallise than the synthetic compound. [Sarges & Witkop J Am Chem Soc 86 1861 1964, 87 2011, 2020 1965.] It has characteristic [] D20 +27.3o (c 1.3, MeOH) and UV max at 282nm ( 22,100). The N-carbamoyldeformyl gramicidine A precipitates from EtOAc/pet ether (b 40-60o). [Beilstein 26 III/IV 4273.]
0 India supplier list of "GRAMICIDIN A"
- Product Name:GramicidinA,HighPurity,Bacillusbrevis-CAS11029-61-1-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:368020 | Purity:GramicidinA,HighPurity,Bacillusbrevis,CAS11029-61-1,isanaturally-occurringioncha
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:GramicidinA
- Products Intro:Brand:pharmaffiliates | Product Number:PA070960000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:GramicidinA,fromBacillusbrevis,≥90%(HPLC)
- Products Intro:Brand:ottokemi | Product Number:G0925 | Purity:90%
- Company Type: Trader
- Country/Region: Mumbai,INDIA
- Product Name:GramicidinA
- Products Intro:Brand:clearsynth | Product Number:CS-T-79573
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:GRAMICIDIN A
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
$1.10/ 1g
- Product Name:Gramicidin A
- Products Intro:Purity: >=90% | CustNote: BOC Sciences also provides custom synthesis services for Gramicidin A.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:GRAMICIDIN A
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceuticals,intermediates,fine chemicals,screening compounds,building blocks
- Product Name:Gramicidin A
- Products Intro:Purity: >=90% | Package: $71.9/1mg;$296.9/5mg;Bulk package | CustNote: 90%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:AFP
- Products Intro:Purity: 95% SDS-PAGE | Package: 1mg;100ug
- Company Type: Trader
- Country/Region: CHINA
-
25mg$315.00
- Product Name:Gramicidin A, High Purity, Bacillus brevis - CAS 11029-61-1 - Calbiochem
- Products Intro:Brand: Sigma-Aldrich | Product Number: 368020 | Purity: Gramicidin A, High Purity, Bacillus brevis, CAS 11029-61-1, is a naturally-occurring ion channel-forming pentadecapeptide. Causes K+/H+ exchange in mitochondria in a non-voltage dependent manner.
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof