JW55
JW55
- CAS:
- 664993-53-7
- MF:
- C25H26N2O5
- MW:
- 434.48
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 572.6±50.0 °C(Predicted)
- Density
- 1.235±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO: soluble15mg/mL, clear
- pka
- 12.41±0.70(Predicted)
- form
- powder
- color
- white to beige
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
- WGK Germany
- 3
Use
JW-55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin. JW-55 inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines. JW-55 reduces cell cycle progression and proliferation in SW480 cells in vitro.
1 India supplier list of "JW55"
- Product Name:JW55
- Products Intro:Brand:sigma aldrich | Product Number:SML0630 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:N-[4-({[4-(4-Methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamide 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.171916
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:JW-55
- Products Intro:Brand:clearsynth | Product Number:CS-T-30191
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:JW55
- Products Intro:Brand:ajchemicals | Product Number:JDH-31648 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:JW55
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:JW 55；JW55
- Products Intro:Purity: 99.62% | Package: 10mg;35USD|25mg;73USD|50mg;119USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:JW55
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: JW55
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:N-(4-(((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)carbamoyl)phenyl)furan-2-carboxamide
- Products Intro:Purity: 95% | CustNote: MC110827
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
- Product Name:JW55
- Products Intro:Purity: 99% | Package: 1KG;25kg;200kg;1000kg Elin | CustNote: g-kg-tons,free sample is available.Bottle/drum/IBC.Advantage products,new batches,regular stock, ready for shipment.
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates