Lansoprazole
Lansoprazole
- CAS:
- 103577-45-3
- MF:
- C16H14F3N3O2S
- MW:
- 369.36
Suppliers by country/region
- India(200)
- CHINA(299)
- Singapore(2)
- United States(69)
- United Kingdom(25)
- Canada(14)
- South Korea(4)
- Germany(9)
- Europe(2)
- France(3)
- Switzerland(3)
- Italy(4)
- Turkey(2)
- Israel(2)
- Spain(10)
- Mexico(3)
- Colombia(1)
- Austria(2)
- Japan(3)
- Brazil(2)
- Slovenia(1)
- Poland(2)
- Belgium(1)
- The Netherlands(1)
- Greece(1)
- Indonesia(1)
- United Arab Emirates(1)
- Jordan(1)
- Malaysia(1)
- Nepal(1)
Company Type
Properties
- Melting point:
- 178-182°C dec.
- Boiling point:
- 555.8±60.0 °C(Predicted)
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, soluble in anhydrous ethanol, very slightly soluble in acetonitrile.
- form
- powder
- pka
- pKa 2.34±0.37 (Occasionally);3.53±0.37 (Occasionally);8.48±0.30 (Occasionally)
- color
- off-white
- Merck
- 14,5362
- BCS Class
- 2
- InChIKey
- MJIHNNLFOKEZEW-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 2
- RTECS
- DD9487500
- HS Code
- 29339900
- Toxicity
- dog,LD,oral,> 2gm/kg (2000mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 35, Pg. 387, 1993.
Use
Lansoprazole is a proton pump inhibitor (PPI) similar to omeprazole that inactivates the hydrogen/potassium-stimulated ATPase pumps in parietal cells, thus inhibiting gastric acid secretion and increasing intragastric pH. It is a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease. Lansoprazole is a racemic mixture of (R)- and (S)-isomers. Dexlansoprazole is an isomer of lansoprazole that has a similar spectrum of activity and toxicities. Lansoprazole therapy is associated with a low rate of transient and asymptomatic serum aminotransferase elevations and is a reported, but very rare cause of clinically apparent liver injury. Lansoprazoles plasma elimination half-life is not proportional to the duration of the drugs effects (i. e. gastric acid suppression). The plasma elimination half-life is 1. 5 hours or less, and the effects of the drug last for over 24 hours after it has been given for 5 days or more. Lansoprazole is a prescription medicine used to treat: gastroesophageal reflux disease (GERD) erosive esophagitis stomach ulcers duodenal ulcers H. Pylori infections Zollinger-Ellison syndrome
200 India supplier list of "Lansoprazole"
- Product Name:Lansoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Lansoprazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Lansoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Lansoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Lansoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:LANSOPRAZOLE NA (25-28%)
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Lansoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Lansoprazole-IP/BP/USP/Ph. Eur
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Lansoprazole EC Pellets
- Products Intro:Purity: 98% | Package: 3MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Lansoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA