LY 2157299
LY 2157299
- CAS:
- 700874-72-2
- MF:
- C22H19N5O
- MW:
- 369.42
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Company Type
Properties
- Melting point:
- 241-242°C
- Boiling point:
- 619.0±55.0 °C(Predicted)
- Density
- 1.40
- Flash point:
- 328.162℃
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 25 mg/ml)
- form
- solid
- pka
- 15.27±0.30(Predicted)
- color
- White
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 45
- HS Code
- 29334900
Use
LY2157299 is a small molecule inhibitor of the TGF-β receptor type 1 kinase (IC50 = 56 nM). It has been used to study the role of TGF-β signaling in chemotherapy-induced expansion of cancer stem-like cells in triple negative breast cancer cell lines and xenografts. LY2157299 has also been shown to inhibit the migration and tumor growth of hepatocellular carcinoma cell lines by disrupting Smad-2 phosphorylation.[Cayman Chemical]
0 India supplier list of "LY 2157299"
- Product Name:Galunisertib
- Products Intro:Brand:sigma aldrich | Product Number:SML2851 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:LY 2157299
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$2.00/ 1kg