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Medroxyprogesterone Acetate

Medroxyprogesterone Acetate

CAS:
71-58-9
MF:
C24H34O4
MW:
386.52

Properties

Melting point:
206-207 °C(lit.)
alpha 
D +61° (in chloroform)
Boiling point:
432.7°C (rough estimate)
Density 
1.0346 (rough estimate)
refractive index 
48 ° (C=1, Dioxane)
storage temp. 
Sealed in dry,2-8°C
solubility 
Practically insoluble in water, freely soluble in methylene chloride, soluble in acetone, sparingly soluble in ethanol (96 per cent)
form 
Solid
color 
White
Water Solubility 
<0.1 g/100 mL at 23 ºC
Merck 
13,5817
BRN 
2066112
BCS Class
2,3,1
Stability:
Stable, but weakly air and light sensitive. Incompatible with strong oxidizing agents.

Safety Information

Symbol(GHS) 

GHS08
Signal word 
Warning
Hazard statements 
H351-H413
Precautionary statements 
P201-P202-P273-P280-P308+P313-P405
Hazard Codes 
Xn
Risk Statements 
40-48
Safety Statements 
22-36/37/39-45
WGK Germany 
3
RTECS 
TU5010000
HS Code 
29372390

Use

A depot preparation containing 150 mg medroxyprogesterone acetate was introduced over 20 years ago for use as a long-acting injectable contraceptive. Subsequently, positive results of carcinogenicity studies carried out in beagle bitches led to refusal of registration in the United States. These findings were later considered irrelevant to contraceptive use in women and the drug was approved by the Food and Drug Administration. Menstrual irregularities are the most common adverse effect associated with depot medroxyprogesterone acetate. Risk-benefit judgements differ significantly from country to country, having regard to differing national circumstances. The preparation is, however, widely available and is included in the WHO Model List of Essential Drugs. (Reference: (WHTAC4) The Use of Essential Drugs, 4th Report of the WHO Expert Committee, 796, , 1990)

32 India supplier list of "Medroxyprogesterone Acetate"

  • Product Name:Medroxyprogesterone 17-acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Medroxyprogesterone Acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: New Delhi,INDIA
  • Product Name:Medroxyprogesterone 17-acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Medroxyprogesterone 17-acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Madhya Pradesh,INDIA
  • Product Name:Medroxyprogesterone17-acetate
  • Products Intro:Brand:sigma aldrich | Product Number:46412 | Purity:VETRANAL?,analyticalstandard
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Medroxyprogesterone 17-acetate 97% (HPLC)
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.070029
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:MedroxyprogesteroneAcetate
  • Products Intro:Brand:synzeal | Product Number:206277402
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:Medroxyprogesterone Acetate
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Medroxyprogesterone Acetate
  • Company Type: Reagent
  • Country/Region: Mumbai,INDIA
  • Product Name:Medroxyprogesterone Acetate
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA

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