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(+/-)-NICOTINE
(+/-)-NICOTINE
- CAS:
- 22083-74-5
- MF:
- C10H14N2
- MW:
- 162.23
Properties
- Melting point:
- -79 °C
- Boiling point:
- 67°C/0.5 mm
- Density
- 1.02 g/mL at 25 °C(lit.)
- Flash point:
- 101 °C
- storage temp.
- Refrigerator
- solubility
- ethanol: 50 mg/mL
- form
- liquid
- pka
- 8.02(at 25℃)
- color
- yellow
- optical activity
- [α]25/D 0°(lit.)
- BRN
- 82108
- Stability:
- Air Sensitive
Safety Information
- Symbol(GHS)
GHS06,GHS09
- Signal word
- Danger
- Hazard statements
- H301-H310-H411
- Precautionary statements
- P262-P264-P273-P280-P301+P310-P302+P352+P310
- Hazard Codes
- T+,N
- Risk Statements
- 25-27-51/53
- Safety Statements
- 36/37-45-61
- RIDADR
- UN 1654 6.1/PG 2
- WGK Germany
- 3
- RTECS
- QS5257500
Use
(+/-)-NICOTINE is an alkaloid isolated from plants. It is an active stimulant, having both addictive and carcinogenic properties. (+/-)-NICOTINE is purified by fractional distillation. Its solubility in EtOH is ~5%. The picrate forms yellow needles from hot H2O and has m 219o. The methiodide has m 219o (from MeOH). [Craig J Am Chem Soc 55 2854 1933, Nakane Hutchinson J Org Chem 43 3922 1978, Beilstein 23/6 V 64.] POISONOUS.
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