Norethindrone
Norethindrone
- CAS:
- 68-22-4
- MF:
- C20H26O2
- MW:
- 298.43
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Company Type
Properties
- Melting point:
- 205-206 °C (lit.)
- Boiling point:
- 379.83°C (rough estimate)
- alpha
- D20 -31.7° (chloroform); D20 -25° (chloroform)
- Density
- 1.0766 (rough estimate)
- refractive index
- 1.4800 (estimate)
- storage temp.
- 2-8°C
- solubility
- chloroform: ≥50 mg/mL, clear, colorless
- form
- powder
- pka
- 13.09±0.40(Predicted)
- color
- white to off-white
- Water Solubility
- 7.043mg/L(25 ºC)
- Merck
- 6697
- BRN
- 1915671
- BCS Class
- 1
- InChIKey
- VIKNJXKGJWUCNN-XGXHKTLJSA-N
Safety Information
- Symbol(GHS)
GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H351-H360FD-H362-H410
- Precautionary statements
- P202-P260-P263-P264-P273-P308+P313
- Hazard Codes
- Xn
- Risk Statements
- 40-36/37/38-20/21/22
- Safety Statements
- 22-36/37/39-45-37/39-26
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
- RTECS
- RC8975000
- HS Code
- 29144000
- Toxicity
- LD50 oral in mouse: 6gm/kg
Use
norethindrone, the discovery of the potentprogestin activity of 17α-ethinyltestosterone (ethisterone) and19-norprogesterone preceded the development of these potentprogestins. both are orally active, with the 17α-ethinyl groupblocking oxidation to the less active 17-one. the rich electrondensity of the ethinyl group and the absence of the 19-methylgroup greatly enhance progestin activity. both compoundswere of great importance as progestin components of oralcontraceptives, although currently, use of norethynodrel isminimal. norethindrone, usp, and norethindrone acetate,usp, are widely used for all the usual indications of the progestins,as well as being components of oral contraceptives.because these compounds retain key features of the testosteronestructure, including the 17β-oh, it is not surprisingthat they possess some androgenic side effects.
50 India supplier list of "Norethindrone"
- Product Name:Norethindrone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Norethindrone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Norethisterone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Norethindrone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Levonorgestrel EP Impurity U
- Products Intro:Purity: 98% | Package: 25mg, 50mg,100mg,200mg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Norethindrone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Norethindrone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Norethisterone
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Norethindrone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Madhya Pradesh,INDIA
- Product Name:Norethindrone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA