Plitidepsin
Plitidepsin
- CAS:
- 137219-37-5
- MF:
- C57H87N7O15
- MW:
- 1110.34
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Properties
- Melting point:
- 152-160°
- alpha
- D -95.9° (c = 1.8 in CHCl3)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- pka
- 11.28±0.70(Predicted)
- form
- Solid
- color
- White to off-white
- InChIKey
- UUSZLLQJYRSZIS-NIORUGPLNA-N
Safety Information
Use
Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activities, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/ DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth.
0 India supplier list of "Plitidepsin"
- Product Name: Plitidepsin
- Products Intro:Purity: 99% | Package: 1kg;8USD|25kg;2USD|100kg;0.8USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
$8.00-0.80 / 1kg
- Product Name:Plitidepsin
- Products Intro:Purity: >98% | CustNote: https://www.alfa-chemistry.com/plitidepsin-cas-137219-37-5-item-290125.htm
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Active Pharmaceutical Ingredient (API),Insect Pheromone,Boronic Compounds,Material & Chemicals,Lipid Compounds