Promazine
Promazine
- CAS:
- 58-40-2
- MF:
- C17H20N2S
- MW:
- 284.4191
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Company Type
Properties
- Melting point:
- 25°C
- Boiling point:
- bp0.3 203-210°
- Density
- 1.1256 (rough estimate)
- refractive index
- 1.6000 (estimate)
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- pKa 9.4(H2O,t =24±1) (Uncertain)
- color
- Off-White to Pale Beige
- Water Solubility
- 14.22mg/L(24 ºC)
- Stability:
- Hygroscopic
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
- Toxicity
- LD50 oral in rat: 350mg/kg
Use
Promazine, 10-[3-(dimethylamino) propyl-(phenothiazine monohydrochloride (Sparine), was introducedinto antipsychotic therapy after its 2-chloro-substitutedrelative. The 2H-substituent vis-à-vis the 2Clsubstituent gives a milligram potency decrease as an antipsychotic,as encompassed in Gordon’s rule. Tendency toEPS is also lessened, which may be significant, especially ifit is decreased less than antipsychotic potency.
4 India supplier list of "Promazine"
- Product Name:Chlorpromazine EP Impurity C
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Promazine Dimer Impurity
- Products Intro:Purity: 98.10 | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Promazine
- Products Intro:Brand:pharmaffiliates | Product Number:PA0347031
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:ChlorpromazineImpurity1
- Products Intro:Brand:synzeal | Product Number:20868303
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Promazine
- Company Type: Reagent
- Country/Region: Haryana,INDIA