Rifapentine manufacturers and suppliers in india

Rifapentine

Properties

Melting point:: 179-1800C

Boiling point:: 969.3±65.0 °C(Predicted)

Density: 1.35±0.1 g/cm3(Predicted)

storage temp.: Sealed in dry,Store in freezer, under -20°C

solubility: methanol: soluble2mg/mL, clear, red to red-brown

form: powder

pka: 4.81±0.70(Predicted)

color: Red

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26

WGK Germany: 3

RTECS: JQ0902000

HS Code: 2941.90.3000

Toxicity: LD50 in mice (mg/kg): >2000 orally; 750 i.p. (Cricchio); LD50 in mice (mg/kg): 3300 orally; 710 i.p. (Aroli)

Use

Rifapentine is a broad spectrum antibiotic highly active against Gram-positive bacteria and Neisseria gonorrhoea. It is reported to be 10 times more active than the structurally related rifampicin against Mycobacrerim fuberculosis. Unlike rifampicin the bioavailability of rifapentine is significantly increased when administered after a meal.