SERTINDOLE
SERTINDOLE
- CAS:
- 106516-24-9
- MF:
- C24H26ClFN4O
- MW:
- 440.94
Suppliers by country/region
Company Type
Properties
- Melting point:
- 95-100°C
- Boiling point:
- 592.1±50.0 °C(Predicted)
- Density
- 1.36
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: >10mg/mL
- form
- solid
- pka
- 14.53±0.20(Predicted)
- color
- off-white
- Merck
- 14,8466
- InChIKey
- GZKLJWGUPQBVJQ-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335-H413
- Precautionary statements
- P261-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- RTECS
- NJ0621100
- HS Code
- 2933.99.6100
Use
Serdolect was launched in the UK for acute and chronic schizophrenia and schizoaffective psychoses. It is synthetically available in three steps from 5chloro-l- (4-fluorophenyl)-l H-indole. Sertindole is selective for the limbic areas of the brain and has a high affinity for the serotinin 5-HT2 receptor where it behaves as an antagonist. It has weak affinity for the α1-adrenergic receptor and no affinity for dopamine D2 receptors. It is as effective as haloperidol but without the extrapyramidal symptoms. This may be a consequence of the fact that it expresses the c-fos protein in a manner different for haloperidol but similar to clozapine. It is non-sedating, long lasting (several days after a single dose) and has an atypical mode of action.
1 India supplier list of "SERTINDOLE"
- Product Name:Sertindole
- Products Intro:Brand:tcichemicals | Product Number:S0942
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Sertindole
- Products Intro:Brand:clearsynth | Product Number:CS-T-42273
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Sertindole
- Products Intro:Brand:pharmaffiliates | Product Number:PA191580000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:SERTINDOLE
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:SERTINDOLE
- Products Intro:Purity: 98% HPLC | Package: 5G;10G;25G;50G;100G;250G;1KG
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Sertindole
- Products Intro:Purity: 99%min | Package: 1kg 5kg 10kg 25kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Sertindole
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chlorogenic acid,Tea polyphenol,Acacetin,Gentiopicroside,Jatrorrhizine
- Product Name:SERTINDOLE
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
$1.10/ 1g
- Product Name:SERTINDOLE； 1-[2-[4-[5-CHLORO-1-(4-FLUOROPHENYL)-1H-INDOL-3-YL]-1-PIPERIDINYL]ETHYL]-2-IMIDAZOLIDINONE
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:Sertindole
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: Sertindole
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms