SINEFUNGIN
SINEFUNGIN
- CAS:
- 58944-73-3
- MF:
- C15H23N7O5
- MW:
- 381.39
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Properties
- alpha
- D25 -2.61° (c = 5 in water); D23 +12 ±2° (c = 0.227 in water)
- Boiling point:
- 783.2±70.0 °C(Predicted)
- Density
- 1.91±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble
- form
- powder
- pka
- pKa (66% DMF): 2.9, 3.9, 8.9, 10.2(at 25℃)
- color
- white to yellow
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 36
- WGK Germany
- 3
- RTECS
- HE3140000
- HS Code
- 29419090
- Toxicity
- LD50 s.c. in mice: 185 mg/kg (Hamill, Hoehn, J. Antibiot.)
Use
Sinefungin, a polar nucleoside antifungal active with broad biological activity, was isolated from a number of species of Streptomyces in the early 1970s. Sinefungin acts by inhibiting a wide range of methyltransferases, including the methylation of bases in DNA and RNA which alters cytosine deamination and gene expression. Sinefungin is widely used as a bioprobe to block methyltransferase-dependent pathways.
0 India supplier list of "SINEFUNGIN"
- Product Name:SCFfromrat
- Products Intro:Brand:sigma aldrich | Product Number:SRP3251 | Purity:recombinant,expressedinE.coli,≥98%(SDS-PAGE),≥98%(HPLC),suitableforcellculture
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:SINEFUNGIN
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chlorogenic acid,Tea polyphenol,Acacetin,Gentiopicroside,Jatrorrhizine
- Product Name:Sinefungin
- Products Intro:Purity: >95% by HPLC | CustNote: BOC Sciences also provides custom synthesis services for Sinefungin.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:Sinefungin
- Products Intro:Purity: 97% | Package: mgs,gs,kgs
- Company Type: Trader
- Country/Region: CHINA
- Main Products: nucleosides,nucleotides,sugars,hosphorylated monomers,impurity
- Product Name:Sinefungin
- Products Intro:Purity: 95% (HPLC) | CustNote: https://reagents.alfa-chemistry.com/product/sinefungin-cas-58944-73-3-13621.html
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Active Pharmaceutical Ingredient (API),Insect Pheromone,Boronic Compounds,Material & Chemicals,Lipid Compounds
- Product Name:Sinefungin
- Products Intro:Purity: NLT 98% | CustNote: MC562073
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
- Product Name:SINEFUNGIN
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:Sinefungin
- Products Intro:Purity: 95% | Package: $266.9/1mg;Bulk package | CustNote: 95%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:Sinefungin
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A869317
- Company Type: Reagent
- Country/Region: CHINA
-
2mg-m$195.00
- Product Name:InSolution Sinefungin - CAS 58944-73-3 - Calbiochem
- Products Intro:Brand: Sigma-Aldrich | Product Number: 567051-M | Purity: An anti-leishmanial nucleoside antibiotic that acts as an S-adenosyl-L-methionine (SAM, AdoMet) methyltransferase-specific inhibitor.
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof