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When a goat is dosed with 14C-tefluthrin orally, extensive metabolism occurs in the goat by ester cleavage and oxidation at a variety of positions on the molecules. Low radioactive residues are detected in the milk, fat, and muscle, with tefluthrin as the largest individual component of the residue. Higher residues are present in the kidney and liver, and only a small percentage of this residue is due to tefluthrin. The remainder in the kidney and liver is a complex mixture of metabolites. In total, eight metabolites are identified in the feces and urine as well as other tissues such as fat, muscle, kidney, and liver.
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