TERREIN
TERREIN
- CAS:
- 582-46-7
- MF:
- C8H10O3
- MW:
- 154.16
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Properties
- Melting point:
- 125-127℃
- Boiling point:
- 327.2±42.0 °C(Predicted)
- Density
- 1.449±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: soluble1-1.10 mg/mL, clear, colorless
- pka
- 11.77±0.60(Predicted)
- form
- A solid
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- WGK Germany
- 3
- HS Code
- 29419000
Use
Terrein is a polar, substituted dihydrocyclopentenone first reported by Raistrick and colleagues in the 1930s and subsequently found in a number of Aspergillus and Penicillium species. For many years the biological profile and mode of action of terrein was unstudied; however, recent research showed that terrein reduces melanin synthesis by reducing tyrosinase production via ERK activation, followed by MITF down-regulation. Terrein also reduces human keratinocyte proliferation by inhibiting ERK and by decreasing the expression of cyclin B1 and Cdc2 complex.
0 India supplier list of "TERREIN"
- Product Name:Terrein
- Products Intro:Brand:sigma aldrich | Product Number:T5705 | Purity:fromAspergillusterreus,≥98%(HPLC)
- Company Type: Trader
- Country/Region: INDIA