(Trifluoromethyl)trimethylsilane
(Trifluoromethyl)trimethylsilane
- CAS:
- 81290-20-2
- MF:
- C4H9F3Si
- MW:
- 142.2
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Properties
- Boiling point:
- 54-55 °C (lit.)
- Density
- 0.962 g/mL at 20 °C (lit.)
- vapor pressure
- 10.98 psi ( 55 °C)
- refractive index
- n
20/D 1.386
- Flash point:
- 14 °F
- storage temp.
- 2-8°C
- solubility
- sol THF, ether, CH2Cl2.
- form
- Liquid
- Specific Gravity
- 0.962
- color
- Clear colorless
- Water Solubility
- Soluble in alcohol, THF, ether, dichloromethane, aromatic and aliphatic hydrocarbons. Soluble in water(with white smokes).
- Sensitive
- Moisture Sensitive
- Hydrolytic Sensitivity
- 4: no reaction with water under neutral conditions
- Merck
- 14,9683
- BRN
- 4241868
- Exposure limits
- ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
- Stability:
- Volatile
- InChIKey
- MWKJTNBSKNUMFN-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS02
- Signal word
- Danger
- Hazard statements
- H225-H261
- Precautionary statements
- P210-P223-P231+P232-P233-P240-P241
- Hazard Codes
- F,Xi,Xn
- Risk Statements
- 11-36/37-19-36/37/38-22-40-14
- Safety Statements
- 16-33-39-26-36-29-36/37
- RIDADR
- UN 1993 3/PG 2
- WGK Germany
- 3
- F
- 10-21
- Hazard Note
- Flammable
- TSCA
- No
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29319090
Use
(Trifluoromethyl)trimethylsilane (TMSCF3) is versatile reagent for trifluoromethylation, such as transition-metal-catalyzed reaction, miscellaneous trifluoromethylation, and addition to carbonyl and imine groups. These reactions are extremely useful approaches in the pharmaceutical and agrochemical industry, because they enhance metabolic stability (metabolic blocking) and alter the compound properties (liphophilicity, binding selectivity).
8 India supplier list of "(Trifluoromethyl)trimethylsilane"
- Product Name:Trimethyl(trifluoromethyl)silane
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Trimethyl(trifluoromethyl)silanesolution
- Products Intro:Brand:sigma aldrich | Product Number:367737 | Purity:0.5?MinTHF
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Trifluoromethyltrimethylsilane 98%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.002406
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:trimethyl(trifluoromethyl)silane
- Products Intro:Brand:thermofisher.in | Product Number:279720010 | Purity:99%
- Company Type: Trader
- Country/Region: Maharashtra,INDIA
- Product Name:(Trifluoromethyl)trimethylsilane
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:(Trifluoromethyl)trimethylsilane
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:(Trifluoromethyl)trimethylsilane
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Trifluoromethyl)trimethylsilane
- Products Intro:Brand:clearsynth | Product Number:CS-T-45739
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:(Trifluoromethyl)trimethylsilane
- Company Type: Reagent
- Country/Region: Andhra Pradesh,INDIA
- Product Name:(Trifluoromethyl)trimethylsilane
- Products Intro:Brand:ajchemicals | Product Number:JDH-56060 | Purity:98%
- Company Type: Trader
- Country/Region: New Delhi,INDIA