URB754
URB754
- CAS:
- 86672-58-4
- MF:
- C16H14N2O2
- MW:
- 266.3
Suppliers by country/region
Company Type
Properties
- Melting point:
- 238-240°C
- Boiling point:
- 434.0±48.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- 3.76±0.20(Predicted)
- form
- Off-white solid.
- color
- White to Off-White
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
- HS Code
- 2934.99.4400
Use
URB754 is a potent, noncompetitive inhibitor of MGL, exhibiting an IC50 of 200 nM for the recombinant rat brain enzyme. It inhibits rat brain fatty acyl amide hydrolase (FAAH) less effectively with an IC50 of 32 μM and binds weakly to the rat CB1 receptor with an IC50 of 3.8 μM. It does not inhibit cyclooxygenase-1 (COX-1) or COX-2 at concentrations up to 100 μM. Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
0 India supplier list of "URB754"
- Product Name:6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one
- Products Intro:Brand:tcichemicals | Product Number:M2572
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:URB754
- Products Intro:Brand:clearsynth | Product Number:CS-T-46149
- Company Type: Trader
- Country/Region: INDIA
- Product Name: URB754
- Products Intro:Purity: 99% | Package: 1KG;7USD
- Company Type: Trader
- Country/Region: CHINA
$7.00/ 1KG
- Product Name:6-methyl-2-(p-tolylamino)-4H-benzo[d][1,3]oxazin-4-one
- Products Intro:Purity: 99% HPLC | Package: 100G;1KG;25KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:URB754
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A25620
- Company Type: Reagent
- Country/Region: CHINA
-
10MG$158.9050MG$584.70
- Product Name:6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one,≥95%(HPLC)
- Products Intro:Brand:Chem-Impex | Product Number:43150 | Purity:≥95%(HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
-
100 mg$392.00
- Product Name:URB754
- Products Intro:Brand：Caymanchem | Product Number：10007691 | Purity：>98%
- Company Type: Trader
- Country/Region: UNITED STATES
-
1g$2368.005g$4958.00
- Product Name:6-Methyl-2-(p-tolylamino)-1H-benzo-[d][1,3]oxazin-4(2H)-one
- Products Intro:Brand: Matrix Scientific | Product Number: 144029 | Purity: 95%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:URB754
- Products Intro:Brand：chiralstar | Product Number：scs-1952
- Company Type: Trader
- Country/Region: UNITED STATES
-
100 mg$350.00
- Product Name:URB754
- Products Intro:Brand：dcchemicals | Product Number：DC8130 | Purity：>98%
- Company Type: Trader
- Country/Region: UNITED STATES