zerumbone
zerumbone
- CAS:
- 471-05-6
- MF:
- C15H22O
- MW:
- 218.33
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Properties
- Melting point:
- 67-69℃
- Boiling point:
- 321.6±42.0 °C(Predicted)
- Density
- 0.887±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥10mg/mL
- form
- powder
- color
- white to off-white
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
- LogP
- 4.168 (est)
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H317-H400
- Precautionary statements
- P273-P280-P302+P352
- Hazard Codes
- Xi,N
- Risk Statements
- 43-50
- Safety Statements
- 36/37-60-61
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
Use
Zerumbone is isolated from the rhizomes of the wild ginger Zingiber zerumbet. It isfound to suppress the proliferation of breast cancer and colon cancer cells and alsoto prevent initiation and promotion of skin cancer in mice. It also suppresses theNF-κB activation and its sequential suppression of IκBα kinase activity, IκBαphosphorylation, IκBα degradation, p65 phosphorylation, nuclear translocation,and acylation. It downregulates the NF-κB-regulated gene products like FLIP, cyclinD1, TRAF1, COX2, Bfl-1/A1, MMP-9, Bcl-xL, ICAM-1, Bcl-2, c-myc, XIAP,survivin, IAP1, and IAP2, and thus, it potentiates apoptosis (Murakami et al. 2002;Sakinah et al. 2007).
0 India supplier list of "zerumbone"
- Product Name:Zerumbone
- Products Intro:Brand:sigma aldrich | Product Number:Z3902 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Zerumbone; Zingiber zerumbe extract
- Products Intro:Purity: >=98% HPLC | Package: 1kg;USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: magnolol,Dihydromyricetin,Macleaya Cordata Extract,corosolic acid,Amygdalin
$0.00/ 1kg