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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Quinoline compounds >1-Chloroisoquinoline

1-Chloroisoquinoline

1-Chloroisoquinoline Structure
  • ₹2449 - ₹15800
  • Product name: 1-Chloroisoquinoline
  • CAS: 19493-44-8
  • MF: C9H6ClN
  • MW: 163.6
  • EINECS:628-561-2
  • MDL Number:MFCD00024134
  • Synonyms:1-Chloroisoquinone;Isoquinoline, 1-chloro-;1-Chloroisoquinoline 95%;1-chloro-1,2-dihydroisoquinoline;1-CHLOROISOQUINOLINE;1-CHLOROISOQUINOLINE, 98.0+%(GC);chloroisoquinoline;1-Chloroisoquinoline, 97+% 5GR
6 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberC2097
  • Product description1-Chloroisoquinoline min. 98.0 %
  • Packaging5G
  • Price₹7600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2097
  • Product description1-Chloroisoquinoline min. 98.0 %
  • Packaging25G
  • Price₹15800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number156744
  • Product description1-Chloroisoquinoline 95%
  • Packaging5G
  • Price₹9060.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number156744
  • Product description1-Chloroisoquinoline 95%
  • Packaging1G
  • Price₹2662.95
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L17831-06
  • Product description1-Chloroisoquinoline, 95%
  • Packaging5g
  • Price₹7863
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L17831-03
  • Product description1-Chloroisoquinoline, 95%
  • Packaging1g
  • Price₹2449
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2097 1-Chloroisoquinoline min. 98.0 % 5G ₹7600 2022-05-26 Buy
TCI Chemicals (India) C2097 1-Chloroisoquinoline min. 98.0 % 25G ₹15800 2022-05-26 Buy
Sigma-Aldrich(India) 156744 1-Chloroisoquinoline 95% 5G ₹9060.53 2022-06-14 Buy
Sigma-Aldrich(India) 156744 1-Chloroisoquinoline 95% 1G ₹2662.95 2022-06-14 Buy
ALFA India ALF-L17831-06 1-Chloroisoquinoline, 95% 5g ₹7863 2022-05-26 Buy
ALFA India ALF-L17831-03 1-Chloroisoquinoline, 95% 1g ₹2449 2022-05-26 Buy

Properties

Melting point :31-36 °C (lit.)
Boiling point :274-275 °C/768 mmHg (lit.)
Density :1.2108 (rough estimate)
refractive index :1.6342 (estimate)
Flash point :>230 °F
storage temp. :Inert atmosphere,2-8°C
pka :2.03±0.30(Predicted)
form :Low Melting Solid, Crystals and/or Chunks
color :White to yellow
Water Solubility :Insoluble in water.
BRN :2996
InChIKey :MSQCQINLJMEVNJ-UHFFFAOYSA-N
CAS DataBase Reference :19493-44-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.

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