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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Acyl halide >4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Structure
  • ₹0
  • Product name: 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
  • CAS: 106261-64-7
  • MF: C13H18Cl2N2O
  • MW: 289.2
  • EINECS:680-808-3
  • MDL Number:MFCD11519983
  • Synonyms:4-(4-Methylpiperizinomethyl)benzoylchloride2HCl;4-(4-Methylpiperizinomethyl)benzoylchloridedihydrochloride;4-(4-METHYLPIPERAZINYLMETHYL)BENZOYL CHLORIDE DIHYDROCHLORIDE;4-[(4-Methyl-1-piperazinyl)methyl]benzoyl chloride dihydrochloride;4-[(4-Methyl-1-piperazinyl)Methyl]benzoyl chloride;Benzoyl chloride,4-[(4-Methyl-1-piperazinyl)Methyl]-, hydrochloride (1:2);4‐[(4‐Methyl‐1‐piperazinyl)‐methyl]‐benzoyl chloride hydrochloride;4-(4-Methylpiperazinylmethyl)benzoyl chloride DiHCl
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>240°C (dec.)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly)
form :Solid
color :White to Off-White
Water Solubility :100vol% at 20℃[vol%]
Stability :Hygroscopic, Moisture Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.

Description

4-((4-Methylpiperazin-1-yl)methyl)benzoyl Chloride Dihydrochloride is an intermediate in the synthesis of Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde (G407010), an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

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Benzoyl chloride Methyl salicylate 4-Methylbenzoyl chloride Sodium chloride 1-Methylpiperazine Benzoyl peroxide 2-Fluorobenzoyl chloride Choline chloride Ammonium chloride Tribenuron methyl 94695-48-4 3-Methylbenzoyl chloride 4-Nitrobenzoyl chloride Methyl bromide

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Suppliers and manufacturers

Rampex Labs Private Limited Vihita Chem Private Limited Molkem Chemicals Shree Jaya Laboratories Pvt. Ltd. Lorven therapeutics Pvt Ltd Basic Pharma Life Science Pvt Ltd VIVAN Life Sciences Pvt. Limited. CLEARSYNTH LABS LTD.
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.