(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
![]() |
- ₹0
- Product name: (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
- CAS: 115104-28-4
- MF: C26H27ClN2O3S2
- MW: 515.09
- EINECS:
- MDL Number:MFCD00797675
- Synonyms:MK-571 SODIUM SALT;MK-571, NA SALT;3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic Acid Sodium Salt;3-[[[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid;L-660711;(3-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)((3-dimethylamino-3-oxopropyl)thio)methyl)thiopropanoic acid;Mk 0571;Mk 0679
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|
Properties
Melting point :65-70°C
Boiling point :712.3±60.0 °C(Predicted)
Density :1.327±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :4.27±0.10(Predicted)
form :Off-white solid.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Boiling point :712.3±60.0 °C(Predicted)
Density :1.327±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :4.27±0.10(Predicted)
form :Off-white solid.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
Symbol(GHS): |
![]() |
||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||||||||||||||||||
Hazard statements: |
|
||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
The cysteinyl leukotrienes (CysLTs), leukotriene (LTC4), LTD4, and LTE4, mediate their actions through two distinct G protein-coupled receptors. LTD4 is the preferred ligand for the CysLT1 receptor, whereas LTC4 and LTD4 bind with approximately equal affinity to the CysLT2 receptor. MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively, which is indicative of CysLT1 receptor-mediated activity in these preparations. MK-571 effectively blocks LTD4 activation of recombinant human and murine CysLT1 receptors but is ineffective at blocking LTC4 or LTD4 activation of the recombinant human or murine CysLT2 receptors.More related product prices
Omarigliptin (MK-3102) Mk-2461 . MK 0557 mk-1064 MK-4101 MK-2206 2HCl SCH900776 MK-1775 C2 DIHYDROCERAMIDE EPA PF-622Related product price
- C2 DIHYDROCERAMIDE
₹14100 - EPA
₹6798.1-128709.25