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11BETA-PROSTAGLANDIN E1

11BETA-PROSTAGLANDIN E1 Structure
  • ₹0
  • Product name: 11BETA-PROSTAGLANDIN E1
  • CAS: 27415-26-5
  • MF: C20H34O5
  • MW: 354.48
  • EINECS:
  • MDL Number:MFCD00084822
  • Synonyms:9ALPHA, 11ALPHA15S-TRIHYDROXY-(8BETA)-PROSTA-5Z, 13E-DIEN-1-OIC ACID;8-ISOPROSTANE;8-EPI PROSTAGLANDIN F2ALPHA;8-EPI PGF2ALPHA;8-ISO PROSTAGLANDIN F2ALPHA;(Z)-7-[(1S,2S,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopenty;8-Isoprostaglandin F2a;8-ISOPROSTAGLANDIN F2ALPHA, >99%
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :531.0±50.0 °C(Predicted)
Density :1.153±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: 3 mg/ml
form :A crystalline solid
pka :4.76±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

8-iso PGF2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine. 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle. Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-46619 (10?6 M) and I-BOP (3 x 10?7 M) with IC50 values of 1.6 x 10?6 M and 1.8 x 10?6 M, respectively.

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Suppliers and manufacturers

CLEARSYNTH LABS LTD.
Career Henan Chemica Co
Aladdin Scientific Shanghai Aladdin Biochemical Technology Co.,Ltd. Nantong Hanfang Biotechnology Co. , Ltd. Shanghai Tongwei Biotechnology Co., Ltd MedChemExpress Beijing Jin Ming Biotechnology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd. amyjetsci