Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

DIACYLGLYCEROL KINASE INHIBITOR II

DIACYLGLYCEROL KINASE INHIBITOR II Structure
  • ₹6007.88 - ₹16908.65
  • Product name: DIACYLGLYCEROL KINASE INHIBITOR II
  • CAS: 120166-69-0
  • MF: C28H25F2N3OS
  • MW: 489.58
  • EINECS:
  • MDL Number:MFCD00069258
  • Synonyms:DIACYLGLYCEROL KINASE INHIBITOR I (R59 949);DIACYLGLYCEROL KINASE INHIBITOR II;R59949, 3-[2-[4-(bis(4-Fluorophenyl)methylene)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone;3-[2-[4-Bis(4-fluorophenyl)methylenepiperidino]ethyl]-2,3-dihydro-2-thioxoquinazolin-4(1H)-one;3-[2-[4-(bis(4-Fluorophenyl)Methylene)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, R59949;DAG Kinase Inhibitor II;DAG Kinase Inhibitor;3-[2-(4-[BIS(4-FLUOROPHENYL)-METHYLENE)-1-PIPERIDINYL)ETHYL]-2,3-DIHYDRO-2-THIOXO-4[1H]-QUINAZOLINONE
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5794
  • Product descriptionDiacylglycerol Kinase Inhibitor II solid
  • Packaging5MG
  • Price₹16908.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number266788
  • Product descriptionDiacylglycerol Kinase Inhibitor II - CAS 120166-69-0 - Calbiochem The Diacylglycerol Kinase Inhibitor II, also referenced under CAS 120166-69-0, controls the biological activity of Diacylglycerol KInase. This small m
  • Packaging5MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD5794
  • Product descriptionDiacylglycerol Kinase Inhibitor II solid
  • Packaging1MG
  • Price₹6007.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D5794 Diacylglycerol Kinase Inhibitor II solid 5MG ₹16908.65 2022-06-14 Buy
Sigma-Aldrich(India) 266788 Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 - Calbiochem The Diacylglycerol Kinase Inhibitor II, also referenced under CAS 120166-69-0, controls the biological activity of Diacylglycerol KInase. This small m 5MG ₹15469.99 2022-06-14 Buy
Sigma-Aldrich(India) D5794 Diacylglycerol Kinase Inhibitor II solid 1MG ₹6007.88 2022-06-14 Buy

Properties

Melting point :228-230 °C
Boiling point :637.1±65.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :0.1 M HCl: slightly soluble
form :solid
pka :11.24±0.20(Predicted)
color :pale yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

DAG Kinase Inhibitor is an inhibitor of DGK (Diacylglycerol kinase; DAG Kinase) and is useful for elucidating the roles of protein kinase C (PKC). DAG Kinase Inhibitor has also been reported to inhibit DGK in several systems such as isolated platelet membranes, whole platelets and ghost erythrocytes. Additional reports have shown to inhibit in a concentration dependent manner. DAG Kinase Inhibitor may also inhibit other pathways such as NADPH and potentially interfere with the lipid-mediated assembly process of oxidase components as reported using a cell-free system. This particular isoform, R59949, has been reported to potentially exhibit selective inhibition of DGK-α.

Related product price