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7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2)

7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2) Structure
  • ₹0
  • Product name: 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2)
  • CAS: 1216720-69-2
  • MF: C23H26ClN5
  • MW: 407.95
  • EINECS:
  • MDL Number:MFCD04039788
  • Synonyms:7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2);SCH 79797 (hydrochloride);infarct,SCH79797 dihydrochloride,SCH-79797 dihydrochloride,SCH-79797,SCH79797,Inhibitor,inhibit,Nonpeptide,thrombin,wortmannin,SCH 79797,antiproliferative,platelets,Protease Activated Receptor (PAR),pro-apoptotic,thrombosis,Thrombin receptors,PAR1,cardioprotection,Apoptosis;N3-Cyclopropyl-7-(4-isopropylbenzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :Store at 2-8°C, protect from light
solubility :Soluble to 25 mM in ethanol and to 50 mM in DMSO
form :Powder
color :White to yellow

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

SCH 79797 is a non-peptide antagonist of proteinase-activated receptor 1 (PAR1). It blocks binding of the high affinity thrombin receptor-activating peptide (haTRAP) (IC50 = 70 nM) as well as platelet aggregation induced by either haTRAP or α-thrombin (IC50 = 0.3 and 3 μM, respectively). SCH 79797 has no activity against PAR2, PAR4, or other receptors involved in platelet activation. It also blocks PAR1 activation on vascular smooth muscle cells and endothelial cells.

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