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12(S)-HHT

12(S)-HHT Structure
  • ₹41349.7
  • Product name: 12(S)-HHT
  • CAS: 54397-84-1
  • MF: C17H28O3
  • MW: 280.4
  • EINECS:
  • MDL Number:MFCD00057833
  • Synonyms:(12S,5Z,8E,10E)-12-Hydroxy-5,8,10-heptadecatrienoic acid;(5Z,8E,10E,12S)-12-Hydroxy-5,8,10-heptadecatrienoic acid;12(S)-HHTrE Lipid Maps MS Standard;12(S)-hydroxy-5(Z),8(E),10(E)-*heptadecatrienoic;12(S)-HYDROXY-5(Z),8(E),10(E)-*HEPTADECA TRIENOIC AC;12(S)-HYDROXYHEPTADECA-5Z,8E,10E-TRIENOIC ACID;12(S)-HYDROXY-(5Z,8E,10E)-HEPTADECATRIENOIC ACID;12(S)-HHT
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 50μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberH1640
  • Product description12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic acid ≥93% (HPLC), ethanol solution
  • Packaging50μG
  • Price₹41349.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) H1640 12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic acid ≥93% (HPLC), ethanol solution 50μG ₹41349.7 2022-06-14 Buy

Properties

Boiling point :451.8±45.0 °C(Predicted)
Density :0.992±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form :ethanol solution
pka :4.75±0.10(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

12(S)-HHTrE is an unusual product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of the human platelet. It is biosynthesized by thromboxane synthase (TX synthase) from prostaglandin H2 (PGH2) concurrently with TXA2. The biological role of 12(S)-HHTrE is uncertain. It is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.

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