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5-Methyltetrahydrofolic acid

5-Methyltetrahydrofolic acid Structure
  • ₹0
  • Product name: 5-Methyltetrahydrofolic acid
  • CAS: 134-35-0
  • MF: C20H25N7O6
  • MW: 459.46
  • EINECS:603-809-2
  • MDL Number:MFCD00900533
  • Synonyms:5-Methyltetrahydropteroyl monoglutamate;5-Methyltetrahydropteroylglutamic acid;N5-Methyltetrahydropteroylglutamate;N-Methyltetrahydrofolate;N-Methyltetrahydrofolic acid;Prefolic A;L-Methyl Folate;5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>300°C (dec.)
Density :1.62±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Aqueous Base (Slightly, Sonicated)
form :Solid
pka :3.51±0.10(Predicted)
color :Pale Beige
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5-Methyltetrahydrofolic acid is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine. The availability of methyl groups is essential for a variety of methylation reactions including the synthesis of DNA and proper neural tube closure. It has been used to restore nitric oxide-generating activity in cases of familial hypercholesterolemia or hyperhomocysteinemia, reducing homocysteine levels and improving vascular endothelial function.

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Suppliers and manufacturers

Allastir Private Limited Meteoric Biopharmaceuticals Pvt. Ltd. CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd Raj Nakra Associates Lifesciences Private Limited Himrishi Herbal K.D.Chem Pharma Shaivya Pharmachem. West Bengal Chemicals Industries Ltd Pharma Affiliates