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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >TIROFIBAN HYDROCHLORIDE MONOHYDRATE

TIROFIBAN HYDROCHLORIDE MONOHYDRATE

₹0
Product name: TIROFIBAN HYDROCHLORIDE MONOHYDRATE
CAS: 142373-60-2
MF: C22H39ClN2O6S
MW: 495.07
EINECS:
MDL Number:MFCD00868210
Synonyms:L 700462;L-Tyrosine, N-(butylsulfonyl)-o-(4-(4-piperidinyl)butyl)-, monohydrochloride;N-(Butylsulfonyl)-o-(4-(4-piperidinyl)butyl)-L-tyrosine monohydrochloride;2-(butylsulfonaMido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid;L-Tyrosine,N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, hydrochloride (1:1);-3-(4-(4-(piperidin-4-yl);butoxy);N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine hydrochloride

Properties Safety Information Description

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy

Properties

Melting point :83-87oC
solubility :Methanol (Slightly)
form :Solid
color :White
CAS DataBase Reference :142373-60-2

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tirofiban was launched as Aggrastat in Switzerland and the US for patients with unstable angina or non-Q-wave myocardial infarction to prevent cardiac ischemic events. Tirofiban is synthesized from (S)-tyrosine by a fourstep process. Tirofiban is a novel highly potent antiplatelet agent that inhibits the interaction of fibrinogen with GPⅡb/Ⅲa, an activated platelet membrane-bound glycoprotein complex. It prevents arterial thrombus formation in a dosedependent manner. Clinical efficacy was highly significant with an absolute and relative risk reduction. In these studies, treatment with tirofiban was well tolerated, without significant adverse effects.

More related product prices

4-(4-Piperidyl)-1-butanol 1-Butanesulfonyl chloride Sodium 1-butanesulfonate 4-PYRIDIN-4-YL-BUTYRIC ACID 4-PYRIDIN-4-YL-BUTAN-1-OL N-Butylsulfonyl-O-(4-(4-pyridinyl)butyl)-L-tyrosine 1134-35-6 4-Chloro-1-butanol D-Tyrosine 4-N-AMYLPYRIDINE Tirofiban L-Tyrosine hydrochloride