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Acetylene-PEG4-biotin conjugate

Acetylene-PEG4-biotin conjugate Structure
  • ₹0
  • Product name: Acetylene-PEG4-biotin conjugate
  • CAS: 1458576-00-5
  • MF: C21H35N3O6S
  • MW: 457.58
  • EINECS:
  • MDL Number:MFCD22380755
  • Synonyms:Acetylene-PEG4-biotin conjugate;Biotin-PEG4-alkyne;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-, (3aR,4R,6aS)-;Biotin PEG4 alkyne,PROTAC Linkers,Inhibitor,BiotinPEG4alkyne,inhibit,Biotin-PEG-4-alkyne
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :55-64 °C
Boiling point :707.1±60.0 °C(Predicted)
Density :1.158±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in Water, DMSO, DCM, DMF
form :Solid
pka :13.90±0.40(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Biotin-PEG4-alkyne is click chemistry biotinylation reagent. The alkyne group is reactive with azide moiety via Click Chemistry reaction to form a stable triazole linkage. PEG arm increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

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