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(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione

(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Structure
  • ₹0
  • Product name: (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
  • CAS: 1486466-31-2
  • MF: C25H30ClFO4
  • MW: 448.95
  • EINECS:
  • MDL Number:MFCD11558988
  • Synonyms:9α-Fluoro-11β-hydroxy-16-β-Methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one;Clobetasol impurity J (PhEur);Clobetasol Related Compound A (USP);Clobetasol Propionate EP Impurity J;Clobetasol Propionate Impurity 10(Clobetasol Propionate EP Impurity J);2-tert-butyl-1'-(7-methyl-3a,7a-dihydro-1H-indazole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one;Clobetasol Propionate USP Related Compound A/(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione;Clobetasol Propionate USP Related Compound A
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>276°C (dec.)
Boiling point :563.7±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Dioxane (Very Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
pka :12.96±0.70(Predicted)
color :White to off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione, is an impurity of Clobetasol (C583490), a topical corticosteroid, and a Glucocorticoid, used as an anti-inflammatory agent.