15(R)-PROSTAGLANDIN E2
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- Product name: 15(R)-PROSTAGLANDIN E2
- CAS: 38873-82-4
- MF: C20H32O5
- MW: 352.47
- EINECS:
- MDL Number:MFCD00135218
- Synonyms:15(R)-PROSTAGLANDIN E2;15-EPI PGE2;9-OXO-11ALPHA,15R-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;XEYBRNLFEZDVAW-GKEZHNTDSA-N;(15R)-PGE2;Dinoprostone EP Impurity A;(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E)-(3R)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid (15-epiPGE2;Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11α,13E,15R)-
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Properties
Boiling point :530.1±50.0 °C(Predicted)
Density :1.148±0.06 g/cm3(Predicted)
solubility :DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)
pka :4.75±0.10(Predicted)
Density :1.148±0.06 g/cm3(Predicted)
solubility :DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)
pka :4.75±0.10(Predicted)
Safety Information
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Description
15(R)-Prostaglandin E2 (15(R)-PGE2) is the C-15 epimer of the naturally occurring 15(S)-PGE2. 15(R)-PGE2 is much less potent than the natural stereoisomer in most biological assays. In hamsters, a dose of 0.20 mg of PGE2 inhibits fertility by 100%, whereas a dose of 1.0 mg of 15(R)-PGE2 inhibits fertility by only 17%. 15(R)-PGE2 occurs as a minor impurity in some pharmaceutical formulations of PGE2 used in obstetrics.Suppliers and manufacturers
Pharma Affiliates
CLEARSYNTH LABS LTD.
Pharmaffiliates Analytics and Synthetics P. Ltd
SynZeal Research Pvt Ltd
Beijing Biocreative Technology Co., Ltd.
ChemStrong Scientific Co.,Ltd
Cayman Chemical Company
Shanghai Yifei Biotechnology Co. , Ltd.
Shanghai Zerui Biotechnology Co., Ltd.
Zhuhai Anzhe Biotechnology Co,Ltd.