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(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid

(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid Structure
  • ₹0
  • Product name: (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid
  • CAS: 1608986-16-8
  • MF: C14H13N3O3
  • MW: 271.27
  • EINECS:
  • MDL Number:MFCD26960588
  • Synonyms:Bortezomib (2R)-Acid;Bortezomib Acid R-Isomer;D-Phenylalanine, N-(2-pyrazinylcarbonyl)-;(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid? (Bortezomib Impurity);(pyrazine-2-carbonyl)-D-phenylalanine;(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid;(2R)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :573.8±50.0 °C(Predicted)
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :soluble in Methanol
form :Powder
pka :13.93±0.46(Predicted)
color :Yellowish

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N-(2-Pyrazinylcarbonyl)-D-phenylalanine is an starting intermediate in the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.

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Suppliers and manufacturers

A.J Chemicals CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates
ShenZhen Trendseen Biological Technology Co.,Ltd.
China National Standard Pharmaceutical Corporation Limited
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
Amadis Chemical Company Limited Guangzhou Dreampharm Biotechnology Co., Ltd.