(R)-Omeprazole Sodium Salt
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- Product name: (R)-Omeprazole Sodium Salt
- CAS: 161796-77-6
- MF: C17H18N3NaO3S
- MW: 367.39789
- EINECS:
- MDL Number:MFCD23160332
- Synonyms:(R)-Omeprazole Sodium Salt ;6-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-;(R)-Omeprazole sodium;6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt;OMeprazole R-IsoMer PotassiuM Salt;R-Omeprazole Sodium Sal;Omeprazole impurity 1/(R)-Omeprazole Sodium Salt/6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole Sodium Salt;Omeprazole Impurity 24
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Properties
Melting point :242-245°C
storage temp. :-20°C Freezer
solubility :DMSO, Water
form :Solid
color :White to Off-White
storage temp. :-20°C Freezer
solubility :DMSO, Water
form :Solid
color :White to Off-White
Safety Information
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| Signal word: | Warning | |||||||
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Description
(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer (esomeprazole magnesium, ). (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).More related product prices
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