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ChemicalBook > Product Catalogue >Analytical Chemistry >Analysis reagents >General Analytical Reagents >(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid Structure
  • ₹4243.4 - ₹40600
  • Product name: (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid
  • CAS: 17257-71-5
  • MF: C10H9F3O3
  • MW: 234.17
  • EINECS:241-292-1
  • MDL Number:MFCD00064200
  • Synonyms:(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(-)-A-METHOXY-A-TRIFLUOROMETHYLPHENYLACETIC ACID;(S)-(-)-MOSHER'S ACID;(S)-(-)-MPTA;(S)-(-)-A-METHOXY-A-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(S)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(S)-(-)-2-METHOXY-2-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(S)-(-)-1-METHOXY-1-(TRIFLUOROMETHYL)PHENYLACETIC ACID
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Brand

  • Sigma-Aldrich
  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 500mg
  • 1G
  • 2.5g
  • 5G
  • ManufacturerSigma-Aldrich
  • Product number318035
  • Product description(S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99%
  • Packaging250MG
  • Price₹4243.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number318035
  • Product description(S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99%
  • Packaging1G
  • Price₹10814.18
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-B23117-ME
  • Product description(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%
  • Packaging500mg
  • Price₹7959
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-B23117-88
  • Product description(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%
  • Packaging2.5g
  • Price₹20317
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM0832
  • Product description(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid [Optical Resolving] min. 98.0 %
  • Packaging1G
  • Price₹13800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM0832
  • Product description(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid [Optical Resolving] min. 98.0 %
  • Packaging5G
  • Price₹40600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number318035
  • Product description(S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99%
  • Packaging250MG
  • Price₹4243.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number318035
  • Product description(S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99%
  • Packaging1G
  • Price₹10814.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number65369
  • Product description(S)-(−)-α-Methoxy-α-trifluoromethylphenylacetic acid for chiral derivatization, LiChropur?, ≥99.0%
  • Packaging250MG
  • Price₹13141.55
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 318035 (S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99% 250MG ₹4243.4 2022-06-14 Buy
Sigma-Aldrich 318035 (S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99% 1G ₹10814.18 2022-06-14 Buy
ALFA India ALF-B23117-ME (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99% 500mg ₹7959 2022-05-26 Buy
ALFA India ALF-B23117-88 (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99% 2.5g ₹20317 2022-05-26 Buy
TCI Chemicals (India) M0832 (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid [Optical Resolving] min. 98.0 % 1G ₹13800 2022-05-26 Buy
TCI Chemicals (India) M0832 (S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid [Optical Resolving] min. 98.0 % 5G ₹40600 2022-05-26 Buy
Sigma-Aldrich(India) 318035 (S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99% 250MG ₹4243.4 2022-06-14 Buy
Sigma-Aldrich(India) 318035 (S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid ≥99% 1G ₹10814.18 2022-06-14 Buy
Sigma-Aldrich(India) 65369 (S)-(−)-α-Methoxy-α-trifluoromethylphenylacetic acid for chiral derivatization, LiChropur?, ≥99.0% 250MG ₹13141.55 2022-06-14 Buy

Properties

Melting point :46-49 °C(lit.)
alpha :D24 -71.8± 0.6° (c = 3.28 in CH3OH)
Boiling point :95-97 °C0.05 mm Hg(lit.)
Density :1.303 g/mL at 25 °C(lit.)
refractive index :n20/D 1.474(lit.)
Flash point :>230 °F
storage temp. :2-8°C
solubility :Readily soluble in hexane, ether, THF, CH2Cl2, benzene.
pka :1.47±0.10(Predicted)
form :Viscous Liquid or Low Melting Solid
Specific Gravity :1.303
color :Clear colorless or white
optical activity :[α]20/D 73±1°, c = 2% in methanol
Sensitive :Hygroscopic
Merck :14,6280
BRN :3591561
CAS DataBase Reference :17257-71-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

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