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5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE

5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE Structure
  • ₹58487.48
  • Product name: 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE
  • CAS: 175135-53-2
  • MF: C10H6ClFN4
  • MW: 236.63
  • EINECS:
  • MDL Number:MFCD00052032
  • Synonyms:5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 97%;5-AMINO-4-CYANO-1-(3-CHLORO-4-FLUOROPHENYL)PYRAZOLE;5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE;5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE;5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole97%;5-amino-1-(3-chloro-4-fluorophenyl)-4-pyrazolecarbonitrile;1H-Pyrazole-4-carbonitrile, 5-amino-1-(3-chloro-4-fluorophenyl)-
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Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberJRD0283
  • Product description5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile AldrichCPR
  • Packaging1G
  • Price₹58487.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) JRD0283 5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile AldrichCPR 1G ₹58487.48 2022-06-14 Buy

Properties

Melting point :153-154
Boiling point :433.3±45.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
pka :-1.59±0.50(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile is an intermediate in the synthesis of Binucleine 2 (B387153). Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. Highly isoform-specific inhibitor of Drosophila Aurora B kinase.

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